S-Adenosyl Methionine, SAMe
S-Adenosyl Methionine is a form of the amino acid methionine. The human body produces all the ademetionine it needs for a balanced health. However, low levels of methionine, folate, or vitamin B-12 can lower ademetionine levels. This chemical is not found in any food source, so to normalize its levels, the use of synthetic version is indicated. SAMe works in the immune system, keeping cell membranes healthy, and it also helps the metabolism of brain chemicals, like serotonin, melatonin, and dopamine
- Origin: Plant Based, Animal Product, Synthetic
- Source: Milk, Eggs, Meat, Fish, Soybean, Vegetables, Synthetic
- Type: Amino Acids
- Age Range: Adults, Seniors
- Toxicity: May be toxic in high doses
- Outcomes: Bone and Joint Health, Energy and Mood, Joint Inflammatory and Stiffness, Depression
What are SAMe benefits?
S-Adenosyl Methionine (SAMe) is the amino acid methionine attached to a molecule of ATP; this molecule circulates in the blood naturally and acts as a ‘methyl donor’. A methyl group in chemistry is simply a carbon molecule (attached to some hydrogens), and donating a methyl group to other molecules can speed up or preserve reactions in the body as a form of metabolic ‘maintenance’. Some studies prove the effectiveness of SAMe on symptoms of osteoarthritis and healing in the elderly. There is also a drop in symptoms of depression and an increase in memory, which reinforces the importance of using SAMe as a supplement. Take our test and find out which nutraceuticals can help you!
Table of relations
Outcome
Sub-Outcome
Consistent effects
Strength of effects
Scientific articles
SAMe and Bone and Joint Health
Bone and joint health are deeply affected by vitamins, hormones and minerals, such as calcium, vitamin D and thyroid hormones. Supplements that affect bone and joint health help their structure and strength, in addition to contributing to the healthy balance of involved nutraceuticals.
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Joint Inflammatory and Stiffness
Joint stiffness and inflammation is the feeling of limited joint movement. This sensation may or may not be caused by weakness and is associated with long periods of immobility. Stiffness is common with arthritis, and inflammation worsens the pain and limits certain movement. The timing and cause of the inflammation and stiffness can only be diagnosed by doctors, but preventive and palliative treatments are options for those who suffer from these complaints.
SAMe and Energy and Mood
Energy and mood are associated with several external and internal factors. Hormone release, brain chemical balance, nutrient metabolism, and several other elements alter the way the body and mind respond to daily activities. The compounds that benefit energy and mood are the ones that help in the balance of all these factors.
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Depression
Depression is a chronic and recurrent psychiatric condition that produces mood changes characterized by deep sadness, mood swings, loss of interest in activities, causing significant impairment in daily life.
Table of negative interactions
Foods
Cheese, Eggs, Meat, Milk, tree-nuts, Yogurt
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