Harjor, Asthi Shrinkhala, Cissus Quadrangularis
Native to certain parts of Asia, Africa, and the Arabian Peninsula, Cissus quadrangularis has long been used as a natural remedy to treat a wide variety of ailments. Since ancient times, people have used it to help treat pain, regulate menstruation, and repair bone fractures. The healing properties of this plant are attributed to its high contents of vitamin C and antioxidant compounds like carotenoids, tannins, and phenols.
- Origin: Plant Based
- Source: Itself
- Type: Herbs, Roots & Barks
- Age Range: Adults
- Toxicity: May be toxic in high doses
- Outcomes: Specific Conditions, Cholesterol and Triglycerides
What are Cissus Quadrangularis benefits?
Cissus quadrangularis, also known as veldt grape, adamantine vine, or devil’s spine, is a plant belonging to the grape family that has been used in traditional medicine to treat bone and joint health, as well as for various female disorders and menopause. The healing properties of this plant are attributed to its high vitamin C content and antioxidant compounds such as carotenoids, tannins, and phenols. Native to certain regions of Asia, Africa, and the Arabian Peninsula, Cissus quadrangularis is also used to treat another wide variety of diseases. According to studies, Cissus quadrangularis has a wide range of identified benefits, helping to treat bones, such as increasing bone mass or accelerating fracture healing rates, as well as relieving joint pain; treat female disorders (menopause, libido, and menstrual disorders); protect against chronic diseases such as heart disease, diabetes, and stroke. Scientific evidence has also shown that Cissus quadrangularis has other health benefits, helping to treat: hemorrhoids, obesity, allergies, asthma, bone loss, gout, diabetes, and high cholesterol.
Table of relations
Outcome
Sub-Outcome
Consistent effects
Strength of effects
Scientific articles
Cissus Quadrangularis and Specific Conditions
Specific body conditions categorize precise areas of our body, such as: Respiratory allergies; Liver; Eye health; Blood pressure; Cholesterol and triglycerides; and Blood glucose control. These areas require specific attention because they are delicate functions related to other parts of the body. Respiratory allergies, for example, are linked to the immune system, and to present an effective nutraceutical, we keep our scientific base up to date.
-
Cholesterol and Triglycerides
Triglycerides and cholesterol are both types of fat present in blood. They play very important roles in the body, such as hormone metabolism and nutrient circulation. In order for them to function properly, they need to be at optimum levels - not too high neither too low. The primary way to keep those good levels is to have a healthy diet, with lots of fiber and balanced fats. But there are some nutraceutics that have been proven to help in this process in a very effective way.
Related videos about Cissus Quadrangularis
Other Herbs, Roots & Barks
Andrographis Paniculata is a plant used in Ayurvedic and Chinese medicine and is widely cultivated in India and China. Its fame has grown from its ...
Ver mais
Ashwagandha is a plant used in Ayurvedic medicine, the traditional Indian medicine. Several parts of the plant are used, but the most common in sup...
Ver maisBacopa is a type of herb that contains nootropic compounds. It has been used traditionally for longevity and cognitive enhancement. Bacopa suppleme...
Ver maisReferences
- ^ a b Gupta AK, Shah N, Thakar AB. Effect of Majja Basti (therapeutic enema) and Asthi Shrinkhala (Cissus quadrangularis) in the management of Osteoporosis (Asthi-Majjakshaya). Ayu. (2012)
- ^ Potu BK, Rao MS, Sirasanagandla SR. Effect of Majja Basti (therapeutic enema) and Asthi Shrinkhala (Cissus quadrangularis) in the management of Osteoporosis (Asthi-Majjakshaya). Ayu. (2012)
- ^ a b c d Kothari SC, et al. Safety assessment of Cissus quadrangularis extract (CQR-300): subchronic toxicity and mutagenicity studies. Food Chem Toxicol. (2011)
- ^ a b c d e Kumar R, et al. CNS activity of aqueous extract of root of Cissus quadrangularis Linn. (Vitaceae). J Diet Suppl. (2010)
- ^ Udayakumar R, Sundaran M, Krishna R. Mineral and biochemical analysis of various parts of cissus quadrangularis linn. Anc Sci Life. (2004)
- ^ a b c d e Aswar UM, et al. Estrogenic activity of friedelin rich fraction (IND-HE) separated from Cissus quadrangularis and its effect on female sexual function. Pharmacognosy Res. (2010)
- ^ a b c Singh G, Rawat P, Maurya R. Constituents of Cissus quadrangularis. Nat Prod Res. (2007)
- ^ a b Kumar M, et al. Anti-osteoporotic constituents from Indian medicinal plants. Phytomedicine. (2010)
- ^ a b c d Aswar UM, Mohan V, Bodhankar SL. Antiosteoporotic activity of phytoestrogen-rich fraction separated from ethanol extract of aerial parts of Cissus quadrangularis in ovariectomized rats. Indian J Pharmacol. (2012)
- ^ a b c d Mehta M, Kaur N, Bhutani KK. Determination of marker constituents from Cissus quadrangularis Linn. and their quantitation by HPTLC and HPLC. Phytochem Anal. (2001)
- ^ a b c Phytochemical Studies on Cissus quadrangularis Linn..
- ^ a b c d Sapsrithong T, et al. Cissus quadrangularis ethanol extract upregulates superoxide dismutase, glutathione peroxidase and endothelial nitric oxide synthase expression in hydrogen peroxide-injured human ECV304 cells. J Ethnopharmacol. (2012)
- ^ a b Stilbene Derivatives from Cissus quadrangularis.
- ^ a b c d e f g Chidambaram J, Carani Venkatraman A. Cissus quadrangularis stem alleviates insulin resistance, oxidative injury and fatty liver disease in rats fed high fat plus fructose diet. Food Chem Toxicol. (2010)
- ^ a b Shah UM, et al. Development and Validation of a Simple Isocratic HPLC Method for Simultaneous Estimation of Phytosterols in Cissus quadrangularis. Indian J Pharm Sci. (2010)
- ^ Chidambara Murthy KN, et al. Antioxidant and antimicrobial activity of Cissus quadrangularis L. J Med Food. (2003)
- ^ a b c Yadav P, Ganeshpurkar A, Rai G. In vitro H(+) -K(+) ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn. Pharmacognosy Res. (2012)
- ^ Odeku OA, Okunlola A, Lamprecht A. Microbead design for sustained drug release using four natural gums. Int J Biol Macromol. (2013)
- ^ Odeku OA, Fell JT. Evaluation of khaya gum as a directly compressible matrix system for controlled release. J Pharm Pharmacol. (2004)
- ^ a b c Oben JE, et al. The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids Health Dis. (2008)
- ^ a b c d Oben J, et al. The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids Health Dis. (2006)
- ^ Bah S, et al. Antiplasmodial and GABA(A)-benzodiazepine receptor binding activities of five plants used in traditional medicine in Mali, West Africa. J Ethnopharmacol. (2007)
- ^ a b c d e Panthong A, et al. Analgesic, anti-inflammatory and venotonic effects of Cissus quadrangularis Linn. J Ethnopharmacol. (2007)
- ^ a b c Bloomer RJ, et al. Cissus quadrangularis reduces joint pain in exercise-trained men: A pilot study. Phys Sportsmed. (2013)
- ^ a b Oben JE, et al. The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress. Lipids Health Dis. (2007)
- ^ a b Muthusami S, et al. Cissus quadrangularis augments IGF system components in human osteoblast like SaOS-2 cells. Growth Horm IGF Res. (2011)
- ^ Mochizuki S, et al. Effects of estriol on proliferative activity and expression of insulin-like growth factor-I (IGF-I) and IGF-I receptor mRNA in cultured human osteoblast-like osteosarcoma cells. Gynecol Endocrinol. (2005)
- ^ a b c d e Muthusami S, et al. Effects of Cissus quadrangularis on the proliferation, differentiation and matrix mineralization of human osteoblast like SaOS-2 cells. J Cell Biochem. (2011)
- ^ a b Potu BK, et al. Petroleum ether extract of Cissus quadrangularis (Linn.) enhances bone marrow mesenchymal stem cell proliferation and facilitates osteoblastogenesis. Clinics (Sao Paulo). (2009)
- ^ a b Parisuthiman D, et al. Cissus quadrangularis extract enhances biomineralization through up-regulation of MAPK-dependent alkaline phosphatase activity in osteoblasts. In Vitro Cell Dev Biol Anim. (2009)
- ^ Upadhya V, et al. Ethnomedicinal plants used to treat bone fracture from North-Central Western Ghats of India. J Ethnopharmacol. (2012)
- ^ a b c d Chopra SS, Patel MR, Awadhiya RP. Studies of Cissus quadrangularis in experimental fracture repair : a histopathological study. Indian J Med Res. (1976)
- ^ a b c Chopra SS, et al. Studies on Cissus quadrangularis in experimental fracture repair: effect on chemical parameters in blood. Indian J Med Res. (1975)
- ^ UDUPA KN, PRASAD GC. FURTHER STUDIES ON THE EFFECT OF CISSUS QUADRANGULARIS IN ACCELERATING FRACTURE HEALING. Indian J Med Res. (1964)
- ^ PRASAD GC, UDUPA KN. EFFECT OF CISSUS QUADRANGULARIS ON THE HEALING OF CORTISONE TREATED FRACTURES. Indian J Med Res. (1963)
- ^ UDUPA KN, PRASAD GC. Cissus quadrangularis in healing of fractures. A clinical study. J Indian Med Assoc. (1962)
- ^ Singh V, et al. Clinical evaluation of cissus quadrangularis and moringa oleifera and osteoseal as osteogenic agents in mandibular fracture. Natl J Maxillofac Surg. (2011)
- ^ a b Potu BK, et al. Anti-osteoporotic activity of the petroleum ether extract of Cissus quadrangularis Linn. in ovariectomized Wistar rats. Chang Gung Med J. (2010)
- ^ Potu BK, et al. Evidence-based assessment of antiosteoporotic activity of petroleum-ether extract of Cissus quadrangularis Linn. on ovariectomy-induced osteoporosis. Ups J Med Sci. (2009)
- ^ Potu BK, et al. Effect of Cissus quadrangularis Linn on the development of osteopenia induced by ovariectomy in rats. Clin Ter. (2011)
- ^ a b Banu J, et al. Inhibition of Bone Loss by Cissus quadrangularis in Mice: A Preliminary Report. J Osteoporos. (2012)
- ^ a b c Srisook K, et al. Anti-inflammatory effect of ethyl acetate extract from Cissus quadrangularis Linn may be involved with induction of heme oxygenase-1 and suppression of NF-κB activation. J Ethnopharmacol. (2011)
- ^ a b c d Bhujade AM, et al. Evaluation of Cissus quadrangularis extracts as an inhibitor of COX, 5-LOX, and proinflammatory mediators. J Ethnopharmacol. (2012)
- ^ Begum VH, Sadique J. Anti histaminic activity of cissus quadragularis. Anc Sci Life. (1999)
- ^ Austin A, Jegadeesan M, Gowrishankar R. In-vitro screening of cissus quadrangularis L. Variant ii against helicobacter pylori. Anc Sci Life. (2003)
- ^ Jainu M, Vijai Mohan K, Shyamala Devi CS. Gastroprotective effect of Cissus quadrangularis extract in rats with experimentally induced ulcer. Indian J Med Res. (2006)
- ^ Jainu M, Devi CS. Gastroprotective action of Cissus quadrangularis extract against NSAID induced gastric ulcer: role of proinflammatory cytokines and oxidative damage. Chem Biol Interact. (2006)
- ^ Antiulcerogenic activities of the Methanolic extract of Cissus quadrangularis in wistar.
- ^ a b c Jainu M, Mohan KV, Devi CS. Protective effect of Cissus quadrangularis on neutrophil mediated tissue injury induced by aspirin in rats. J Ethnopharmacol. (2006)
- ^ a b Jainu M, Vijaimohan K, Kannan K. Cissus quadrangularis L. extract attenuates chronic ulcer by possible involvement of polyamines and proliferating cell nuclear antigen. Pharmacogn Mag. (2010)
- ^ Shin VY, et al. Cigarette smoke extracts delay wound healing in the stomach: involvement of polyamine synthesis. Exp Biol Med (Maywood). (2002)
- ^ Yetkin G, et al. The healing effect of TGF-alpha on gastric ulcer induced by acetylsalicylic acid in rats. Int J Pharm. (2004)
- ^ Jainu M, Shyamala Devi CS. Attenuation of neutrophil infiltration and proinflammatory cytokines by Cissus quadrangularis: a possible prevention against gastric ulcerogenesis. J Herb Pharmacother. (2005)
- ^ Viswanatha Swamy AH, et al. Evaluation of hepatoprotective activity of Cissus quadrangularis stem extract against isoniazid-induced liver damage in rats. Indian J Pharmacol. (2010)
- ^ Swamy AH, et al. Hepatoprotective Effect of Cissus quadrangularis Stem Extract Against Rifampicin-induced Hepatotoxicity in Rats. Indian J Pharm Sci. (2012)
- ^ Panpimanmas S, et al. Experimental comparative study of the efficacy and side effects of Cissus quadrangularis L. (Vitaceae) to Daflon (Servier) and placebo in the treatment of acute hemorrhoids. J Med Assoc Thai. (2010)
- ^ Pharmacognostic and traditional properties of Cissus quadrancularis Linn -An overview.
- ^ a b Potu BK, et al. Petroleum ether extract of Cissus quadrangularis (LINN) stimulates the growth of fetal bone during intra uterine developmental period: a morphometric analysis. Clinics (Sao Paulo). (2008)
- ^ a b CISSUS QUADRANGULARIS PLANT EXTRACT ENHANCES THE DEVELOPMENT OF CORTICAL BONE AND TRABECULAE IN THE FETAL FEMUR.
- ^ a b Subchronic toxicity of Cissus quadrangularis Linn.
- ^ Sivaswamy SN, et al. Mutagenic activity of south Indian food items. Indian J Exp Biol. (1991)